With regards to the Seinaru perk discussion, don't forget that at the Invincible Drifter, single-use perks packs are sold. It's not ideal given that I'm sure you'd rather use your perks, but just know that you have back-up options!

Item Directory
[P:Blessed Charm] - Grants 1 use of the Seinaru Perk.
Purchased/found: Invincible Drifter: $200 SP$