GraphicsGale. :] I also selected Photoshop because I use that for palette editing and saving the actual sprite with, because I'm weird like that. I don't actually sprite in Photoshop; I just edit what I've already sprited in GG. :]
Paint (and the like)
Paint.NET
GraphicsGale
Aseprite
Photoshop (and the like; more advanced image editing software)
GIMP
Other (Please specify)
Bookmarks