Quote Originally Posted by Noblejanobii View Post
It can. There's three different types of runs you can do and for the most part there's something a little different every time but not always.
Actually there's something even deeper too. You get a set number value in your coding when you start playing. Depending on your value, you may get different things to happen. It'll determine certain things that may be hidden like some secret doors, hidden characters, or dialogues. So in a sense, each run could be different no matter what type of playthrough you're doing. Tends to only work in Pacifist though.